Nael A. McCarty, PhD


Marcus Professor

Cystic Fibrosis


Emory+Children's Cystic Fibrosis Center of Excellence

Phone: 404-727-3654


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Research Interests

Research in the McCarty lab focuses on Cystic Fibrosis (CF), the most common lethal genetic disease among U.S. Caucasians and the second most common genetic disease among all American children.  CF is characterized by recurrent pulmonary bacterial infections, often by many species of bacteria but typically including Pseudomonas aeruginosa and Staphylococcus aureus.  As patients age, often these become represented by strains that are multiply drug resistant.  McCarty's own research focuses on basic and translational research into the mechanisms that tie loss of function of the CFTR chloride channel (the locus of the primary defect in CF), and how this leads to great increases in bacterial burden when CF patients also develop CF-related diabetes.